Bupleurum root

Ingredient Profile

Modern Research Perspective

Bupleurum roots contain saikosaponins, volatile oils, flavonoids, and other constituents. Cell and animal studies have explored immune, inflammatory, hepatic, and stress-related mechanisms, but composition and safety vary by species, extraction, and dose.

Clinical evidence is heterogeneous and frequently involves combined interventions. Bupleurum-associated liver injury has been reported, so dose, liver monitoring, processing, interactions, and long-term safety require caution.

Traditional Function

In traditional Chinese medicine, Bupleurum Root is bitter, pungent, and slightly cold. It is used to harmonize the exterior and interior, regulate Liver qi, raise yang, and relieve alternating fever patterns. Its use depends on the individual pattern and authenticated species.