Licorice root

Ingredient Profile

Modern Research Perspective

Licorice Root contains triterpenoid saponins such as glycyrrhizin, flavonoids, and other constituents. Cell and animal studies have explored anti-inflammatory, antiviral, mucosal, metabolic, and hepatoprotective mechanisms. Evidence varies by species, processing, extract, and dose.

Human studies are heterogeneous and often use combined preparations. Excessive or prolonged glycyrrhizin exposure may cause sodium retention, potassium loss, hypertension, and drug interactions; clinical benefit and safety require dose-aware supervision.

Traditional Function

In traditional Chinese medicine, Licorice Root is sweet and neutral, with a warming tendency when processed. It is used to tonify the Spleen and Qi, moisten the Lung, relieve spasm and pain, clear heat and toxicity, and harmonize other herbs. Its use depends on pattern, dose, and whether the material is raw or processed.